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Clinical Research

An Evidence Based Product

Scientific evidence from independent and university-based research centers shows that the Waterpik water flosser is an easy and more effective alternative compared to string floss and interdental flossers.

To see all research abstracts, view or download our Clinical Research Summary (PDF)


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Comparison of Waterpik™ Water Flosser with Precision Tip to Phillips Sonicare Power Flosser with Quad Tip

WaterpikTM Water Flosser with Precision Tip Statistically Significantly More Effective at Improving Oral Health than the Phillips Sonicare Power Flosser with Quad Tip At Four Weeks

Lyle, DM, Qaqish JH, Goyal, CR, Schuller R, Jahn, CA. *Data on file, 2023

Comparison of Waterpik™ Sensonic™ Complete Care to Brushing Alone

WaterpikTM SensonicTM Complete Care is up to 3x as Effective as Brushing Alone for Improving Gingival Health and up to 5X as Effective for Removing Plaque in Hard-to-Reach Areas

Lyle, MD, Qaqish JG, Goyal, CR, Schuller R. *Data on file, 2023

Comparison of Waterpik™ water flosser to Oral B® Advanced and string floss

WaterpikTM Water Flosser Up to 2X as Effective as Traditional Brushing & Flossing for Removing Plaque & Reducing Bleeding

Lyle, DM, Qaqish JH, Goyal CR, Schuller R. Int J Dent Hyg, 2023;21:659-668.

Results of using the Waterpik™ Sensonic™ toothbrush vs. manual toothbrush

Waterpik SensonicTM Electric Toothbrush: Up to 4x as Effective as Manual Toothbrushing at Reducing Plaque in Hard-to-Reach Areas

Lyle, DM, Qaqish JH, Goyal CR, Schuller R. 2023; *Data on file.

Comparison of sonic-flossing toothbrush to brushing and flossing on inflammation

WaterpikTM Sonic-FusionTM: Up to 2X as Effective as Regular Brushing & Flossing for Improving Gingival Health

Lyle DM, Qaqish JG, Goyal CR, Schuller R. IADR/AADR/CADR General Session & Exhibition. Presented at IADR Virtual Oral Session, July 24, 2021. Submitted for publication.

Improvement in CHX and pocket depth with Waterpik Water Flosser vs. rinsing

WaterpikTM Water Flosser: Using the Water Flosser to Deliver a Dilute of CHX Improves Periodontal Pocket Depth and Clinical Attachment Levels better than rinsing with CHX

Jain R, Chaturvedi R, Pandit N, Grover V, Lyle DM, Jain A. J Indian Soc Periodontol 2020; 24(4):348-353. Study conducted at Institute of Dental Services, Panjab University, Chandigarh, India

Severity of Mucositis reduced with Waterpik Water Flosser compared to ROH

WaterpikTM Water Flosser: Significantly More Effective at Reducing the Severity of Mucositis

Bunk D, Eisenburger M, Hackl S, Eberhard J, Stiesch M, Grischke J. Clin Oral Implant Res 2020; 00:1-13. doi:10.1111/clr.13638. https://onlinelibrary.wiley.com/doi/full/10.1111/clr.13638?af=R. Study conducted at the Hannover Medical School, Hannover, Germany.

Results of using Waterpik™ water flosser on titanium implants

WaterpikTM Water Flosser: Removes > 90% Of Biofilm On Titanium Implant Surface Disc; Better Than CHX, Titanium Brushes And Nylon Brushes

Kotsakis G, Black R, Kum J et al. J Periodotol 2020; 1-12. DOI: 10.1002/JPER.20-0186. https://doi.org/10.1002/JPER.20-0186. Conducted at University of Washington, Seattle, USA.

Waterpik Water Flosser + electric toothbrush vs. electric toothbrush alone

The WaterpikTM Water Flosser Significantly Improves Oral Health Benefits Over a High-End Oscillating Electric Toothbrush

Lyle, DM, Goyal CR, Qaqish JG, Schuller R. Compend Contin Ed Dent 2020; 41(3):170-177. Epub Jan 1, 2020

Pocket and marginal probing bleeding: Waterpik water flosser vs. interdental brush

The WaterpikTM Water Flosser: Significantly More Effective than Interdental Brush for Improving Gingival Health

Slot DE, Lyle DM, Van der Sluijs E, Hennequin-Hoenderdos N, Van der Weijden F. J Dent Res 2018; 97(Special Iss. B): Abstract #0622 (www.iadr.org). Conducted at Academic Center for Dentistry Amsterdam (ACTA), Netherlands.

Safety comparison of Waterpik water flosser vs. string floss vs. toothbrush

WaterpikTM Water Flosser: Safe and Effective up to 100 psi

Goyal CR, Lyle DM, Qaqish JG, Schuller R. Evaluation of the safety of a water flosser on gingival and epithelial tissue at different pressure settings. Compend Contin Ed Dent 2018; 39(Suppl. 2):8-13.

Comparison: Manual toothbrush vs. Waterpik Water Flosser

The WaterpikTM Water Flosser: Adding a WaterpikTM Water Flosser to a Manual Toothbrush is up to 3.1 Times as Effective as Brushing Alone

Goyal, CR, Lyle DM, Qaqish JG, Schuller R. Evaluation of the Addition of a Water Flosser to Manual Brushing on Gingival Health. J Clin Dent 2018; 29(4):81-86. Study conducted at All Sum Research Center LTD, Mississauga, Ontario, Canada.

Comparison of Waterpik Sonic-Fusion vs. Sonicare DiamondClean

WaterpikTM Sonic-FusionTM: Significantly More Effective than Sonicare® DiamondClean for Removing Plaque and Improving Gingival Health

Goyal CR, Qaqish, JG, Schuller R, Lyle D. Compend Contin Educ Dent. 2018;39(suppl 2):14-22.

Waterpik Sonic–Fusion vs. traditional brushing and flossing

WaterpikTM Sonic-FusionTM: Twice as Effective as Regular Brushing & Flossing for Removing Plaque and Improving Gingival Health

Qaqish JG, Goyal CR, Schuller R, Lyle DM. Compend Contin Educ Dent. 2018;39(suppl 2):14-22.

Waterpik™ Triple Sonic Toothbrush vs. manual toothbrush stain removal comparison

WaterpikTM Complete Care Triple Sonic Toothbrush: 9 Times As Much Stain Removal As A Regular Toothbrush

Milleman JL, Milleman KR, Battershell K, Schuller R, Lyle DM. Study conducted at Salus Research, Fort Wayne, IN. 2016.

Gingival health comparison: Waterpik™ water flosser vs. Interdental Brush

The WaterpikTM Water Flosser: Significantly More Effective than Interdental Brushes for Improving Gingival Health

Goyal CR, Lyle DM, Qaqish JG, Schuller R. J Clin Dent 2016; 27: 61-65.

Comparison of Waterpik water flosser vs. interdental brushing

The WaterpikTM Water Flosser: Significantly More Effective than Interdental Brushes for Removing Plaque

Lyle DM, Goyal CR, Qaqish JG, Schuller R. J Clin Dent 2016; 27(1): 23-26.

WaterpikTM Water Flosser: Unequivocally Proven Safe in Clinical Studies Over 5 Decades

Jolkovsky DL et al. Compendium of Continuing Education in Dentistry 2015; 36(2):2-5.

Waterpik Water Flosser vs. subgingival minocycline treatment

WaterpikTM Water Flosser: An Effective Alternative to Subgingival Antibiotic Treatment for Periodontal Maintenance Patients

Genovesi AM, Lorenzi C, Lyle DM et al. Minerva Stomatol 2013; 62(Suppl. 1 to NO. 12):1-9. Study conducted at the Tuscan Stomatologic Institute, Department of Dentistry, Versilia General Hospital, Lido di Camaiore (LU), Italy

Waterpik water flosser vs. string floss in improving gingival health around implants

WaterpikTM Water Flosser: More Than 2 Times as Effective as String Floss for Implant Patients

Magnuson B, Harsono M, Stark PC, et al. Compend of Contin Ed in Dent 2013; 34(Special Issue 8):2-7. Study conducted at Tufts University, School of Dental Medicine, Boston, Massachusetts.

Stain reduction: Waterpik Whitening Water Flosser vs. tooth brushing alone

WaterpikTM Whitening Water Flosser: Improved Stain Removal Over Tooth Brushing Alone

Milliman JL, Milleman KR, Battershell K, Lyle DM. Study conducted at Salus Research, Fort Wayne, IN. 2014

Waterpik™ water flosser vs. string floss in plaque removal comparison

WaterpikTM Water Flosser: Significantly More Effective than String Floss for Removing Plaque

Goyal CR, Lyle DM, Qaqish JG, Schuller R. J Clin Dent 2013;24(2):37-42. Study conducted at BioSci Research Canada, Ltd., 3

Traditional dental floss vs. Waterpik water flosser in reducing gingival bleeding 

WaterpikTM Water Flosser: Twice as Effective as String Floss for Reducing Gingival Bleeding

Rosema NAM et al. The effect of different interdental cleaning devices on gingival bleeding. J Int Acad Periodontol 2011; 13(1):2-10.

Results of using Waterpik water flosser on plaque biofilm removal

WaterpikTM Water Flosser Removes 99.9% of Plaque Biofilm After 3-Second Treatment

Gorur A, Lyle DM, Schaudinn C, Costerton JW. Compend Contin Ed Dent 2009; 30 (Suppl 1):1 - 6.

Comparison of plaque removal for orthodontic patients

WaterpikTM Water Flosser: 3 Times as Effective as String Floss for Orthodontic Patients

Sharma NC, Lyle DM, Qaqish JG, et al. Am J Ortho Dentofacial Orthop 2008; 133(4):565-571. Study conducted at BioSci Research Canada, Ltd., Mississauga, Ontario, Canada.

Brushing and Waterpik water flosser reduce gingivitis

WaterpikTM Water Flosser: Over 50% More Effective than String Floss for Reducing Gingivitis

Barnes CM, et al. J Clin Dent, 2005; 16(3): 71-77. Study conducted at the University of Nebraska Medical Center, College of Dentistry, Lincoln, Nebraska.

Routine oral hygiene vs. Waterpik™ water flosser for diabetic patients comparison

WaterpikTM Water Flosser: Significant Reduction in Plaque Biofilm, Gingivitis, and Bleeding for Patients with Diabetes

Al-Mubarak S, Ciancio S, Aljada A, et al. J Clin Periodontol 2002; 29:295-300. Study conducted at the University of Buffalo, School of Dental Medicine.

Waterpik water flossers reduce gingival bleeding and inflammation

Delivering CHX with the WaterpikTM Pik PocketTM Tip is More Effective than Rinsing with CHX for Implant Maintenance

Felo A, Shibly O, Ciancio S, Lauciello F, Ho A. Am J Dent 1997; 10:107-110

28 Research Articles Match